Journal of Tissue Science and Engineering

Shicheng Sun

Publications

• Mini Review
  Biomaterials for Promoting Wound Healing in Diabetes
  Author(s): Juan Liu, Huaiyuan Zheng, Xinyi Dai, Shicheng Sun, Hans-Günther Machens and Arndt F SchillingJuan Liu, Huaiyuan Zheng, Xinyi Dai, Shicheng Sun, Hans-Günther Machens and Arndt F Schilling
  
  Impaired wound healing is the leading cause of non-traumatic lower limb amputation in people with diabetes mellitus. Skin substitutes engineered from biomaterials currently play an important role in the healing process of diabetic wounds, especially those wounds that fail to show progress after standard wound care. This article summarizes current developments of biomaterials used for promoting the wound healing process in either diabetic animal models or patients with diabetes mellitus. Those biomaterials can be categories into tissue-derived scaffolds, hydrogel-based biomaterials and biomaterials with controlled-release of signaling molecules. Tissue-derived scaffolds maintain perfect extracellular matrix architectures for three-dimensional cell growth and rebuilding of multi-layer tissue structures within scaffolds after implantation. Hydrogel-based biomaterials are engineered to re.. Read More»
  DOI: 10.4172/2157-7552.1000193

  Abstract PDF