Japan
Research Article
Significance of Cytological Findings of Neuroblastomas: Rosette Arrangement and Neuropil Structure
Author(s): Nobuyuki Fukudome, Fumikazu Kimura, Shigenari Arita, Chamidu Atupelage and Kunio MizuguchiNobuyuki Fukudome, Fumikazu Kimura, Shigenari Arita, Chamidu Atupelage and Kunio Mizuguchi
Objectives: Improve treatment outcomes and clarify the biological characteristics of neuroblastoma, development of an international histological classification started several years ago. Aiming at the establishment of a cytology criteria corresponding to the new histological classification, we investigated a criteria comparing lesions related to neuroblastoma on referring to the morphological indices of neuroblastoma reported in the international classification.
Methods: Several tumor specimens were investigated: 37 cases of neuroblastoma (undifferentiated type: 3, poorly differentiated type: 34), 3 cases of ganglioneuroblastoma (mixed type: 2, nodular type: 1), and one case of ganglioneuroma. Stamp cytology samples were prepared from cut surfaces of the tumors and then stained to the Papanicolaou method.
Results: In n.. Read More»
DOI:
10.4172/2157-7099.1000357
Journal of Cytology & Histology received 2334 citations as per Google Scholar report