Nuclear Medicine & Radiation Therapy

Shinji Tsudou

Publications

• Research Article
  Accumulated Dose of Intensity-Modulated Radiotherapy for Head and Neck Cancer Using Deformable Registration of Two Sets of Computed Tomography Images
  Author(s): Shinji Tsudou, Hideki Takegawa, Yoshihiro Ueda, Masayoshi Miyazaki, Ryota Nakashima, Masaki Suga, Hodaka Numasaki, Masaaki Takashina, Masahiko Koizumi, Teruki Teshima and Kinji NishiyamaShinji Tsudou, Hideki Takegawa, Yoshihiro Ueda, Masayoshi Miyazaki, Ryota Nakashima, Masaki Suga, Hodaka Numasaki, Masaaki Takashina, Masahiko Koizumi, Teruki Teshima and Kinji Nishiyama
  
  Purpose: The aim of this study was, using deformable image registration (DIR), to evaluate alteration of dose distribution caused by patient’s anatomical structure changes during a two-phase intensity-modulated radiotherapy (IMRT). Methods: IMRT consisted of an initial plan delivering 53 Gy to gross tumor volume (GTV) and 45 Gy to elective volumes and a boost plan delivering 16.96 Gy to GTV. The subjects were 10 patients with head and neck cancer who underwent computed tomography (CT) scans twice (first CT before treatment and second CT before boost). A sum of the initial and the boost plans for the first CT was Original total plan. Using DIR, the original boost and a modified new boost plan were recalculated on the second CT and summed with the initial plan to create total plans: DIR plan and modified DIR plan. Results: Mean dose (Dmean) of the ipsilateral and c.. Read More»
  DOI: 10.4172/2155-9619.1000264

  Abstract PDF