Journal of Bioengineering & Biomedical Science

Shin-Wei Wang

Publications

• Research Article
  Human Amnion-derived Pluripotent Stem Cells as a Promising Source for Regenerative Medicine and Tissue Engineering
  Author(s): Shigeo Saito, Shin-Wei Wang, Chia-Chen Ku, Chen-Lung Steve Lin, Deng-Chyang Wu, Yoshinobu Murayama and Kazunari K.YokoyamaShigeo Saito, Shin-Wei Wang, Chia-Chen Ku, Chen-Lung Steve Lin, Deng-Chyang Wu, Yoshinobu Murayama and Kazunari K.Yokoyama
  
  Stem cells are undifferentiated cells that can renew themselves and generate specialized cell types with specific functions in the body. Patient- specific pluripotent stem cells might offer a limitless source for transplantable cells and tissues to treat sufferer without causing immune-rejection. Current reprogramming methods to generate pluripotent stem cells involve viral transduction or plasmid transfection that rely upon transient expression of the reprogramming factors without integration of ectopic DNA into the genome. However, the generation of stem cells with high efficiency and safety should be needed for the clinical use. We established human amnion-derived pluripotent cells (HAPCs) and HAPCs derived induced pluripotent stem cells. These cells expressed phenotypic marker characteristics of stem cells. Furthermore, HAPCs contributed to the formation of chimeric embryoid bod.. Read More»
  DOI: 10.4172/2155-9538.S2-005

  Abstract PDF