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Case Report
Systematic Review of the Risk of Permanent Alopecia with Docetaxel
Treatment for Breast Cancer
Author(s): Shirin Nezafat NaminiShirin Nezafat Namini
Aim: The most commonly reported adverse reactions of docetaxel are neutropenia, anaemia, alopecia, nausea, vomiting, stomatitis, diarrhoea and asthenia. Alopecia is a distressing side-effect of cancer treatment and can have a significant negative impact on self-esteem and quality of life. The incidence of permanent alopecia with docetaxel is unclear. We reviewed available evidence relating to permanent alopecia associated with docetaxel given for the treatment of breast cancer. Method: A full literature search was performed using Medline with key words docetaxel and alopecia. Studies were included if they reported the use of docetaxel either alone or in combination regimens in breast cancer and provided information on permanent alopecia. Results: In total three papers were found. Tallon et al. reported a case of permanent alopecia in a 72-year-old caucasian female who was treated with.. Read More»
DOI:
10.4172/2165-7920.1000851
Journal of Clinical Case Reports received 1345 citations as per Google Scholar report