Journal of Bioanalysis & Biomedicine

Shivaleela P. Upashe

Publications

• Research Article
  Antidiabetic and Antioxidant Activity of Rubus apetalus Poir. and Rubus steudneri Schweinf. Leaf Extract on Alloxan Induced Diabetes Mellitus
  Author(s): Raghavendra HL, Shivaleela P. Upashe, David Rafael Abreu Reyes and Juliana F. FlorianoRaghavendra HL, Shivaleela P. Upashe, David Rafael Abreu Reyes and Juliana F. Floriano
  
  Background and objective: Chronic hyperglycemia in diabetes determines the overproduction of free radicals, and evidence is increasing that these contribute to the development of diabetic complications. Aim of the present study was to evaluate the antidiabetic and antioxidant activity of R. apelatus Poir. and R. steudneri Schweinf leaf extract in alloxan induced diabetic rats. Methods: The powdered materials of the R. apelatus Poir. and R. steudneri Schweinf were extracted by maceration process and the extract was used for the study. Single oral dose of 2000 mg/kg body weight of both the extracts were evaluated for acute toxicity. This study evaluated 150 and 300 mg/kg body weight of R. apelatus Poir. and R. steudneri Schweinf leaf extract for given orally for 21 days for its antidiabetic.. Read More»
  

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