Journal of Bioengineering & Biomedical Science

Shoichiro Ozaki

Publications

• Research Article
  2-Aminoethyl Diphenylborinate (2-APB) Analogues: Part 3 - Regulators of Huntington Aggregation and Transglutaminase
  Author(s): Shoichiro OzakiShoichiro Ozaki
  
  Huntington aggregation inhibitory activities and transglutaminase inhibitory activities of 2APB analogues were measured. 2-APB analogues regulated the Huntington aggregation. This fact provided an example that 2-APB analogues can regulate cellular process. Diphenyl (aminoacidonate N,O) boranes, which are effective regulator of Ca2+ release and cellular process, were effective regulators of Huntington aggregation. It was also found that many of 2-APB analogues have moderate transglutaminase inhibition activities 2-Aminoethyl di(4-trifluorophenyl) borinate is a good transglutaminase regurator... Read More»
  DOI: 10.4172/2155-9538.1000131

  Abstract PDF