Journal of Bioengineering & Biomedical Science

Shoichiro Ozaki

Publications

• Review Article
  Chemical Approach to Signal Transduction by Inositol Triphosphate
  Author(s): Shoichiro OzakiShoichiro Ozaki
  
  Berridge discovered that inositol 1,4,5-trisphophate (IP3) was generated at the cell surface in response to cell stimulation and functioned as a second messenger to release Ca2+ from internal stores. Ozaki et al. succeeded in the first total synthesis of optically active IP3 by 13 steps. He supported the signal transduction studies by supplying necessary reagents such as IP3, other IPx, phosphatidyl inositol, new synthetic methods and reagents. He discovered the regulators of Ca2+ release and consequent cellular processes... Read More»
  DOI: 10.4172/2155-9538.1000133

  Abstract PDF