Cancer Science & Therapy

Signed Prieto

Publications

• Research Article
  Fractal and Euclidean Geometrical Diagnosis of Cervix Cytology
  Author(s): Javier Rodríguez Velásquez, Signed Prieto, Catalina Correa, Fernando Polo and Paula LópezJavier Rodríguez Velásquez, Signed Prieto, Catalina Correa, Fernando Polo and Paula López
  
  Background: Conventional methods for evaluation of cervix cytology show reproducibility problems. To solve this, there was developed a diagnostic methodology based on fractal and euclidean geometry, mathematically differentiating normality, L SIL and H SIL. Objective: The aim of the present work is to confirm the clinical applicability of such diagnostic in a blind study. Methods: The clinic diagnosis of 15 normal cells, 15 ASCUS, 15 L SIL and 15 H SIL was masked. Cellular nucleus and cytoplasm were evaluated calculating fractal dimension, number of spaces occupied by the frontier and number of pixels occupied by the surface of each object. The mathematical diagnosis was established and compared with the conventional diagnosis, calculating specificity, sensibility, negative likelihood ratio .. Read More»
  DOI: 10.4172/1948-5956.1000253

  Abstract PDF