Journal of Cytology & Histology

Silva ME

Publications

• Research Article
  Cigarette Smoke Causes Changes in Liver and Spleen of Mice Newborn Exposed During Pregnancy
  Author(s): Diniz MF, Dourado VA, Silva ME, Pedrosa ML, Bezerra FS and Wanderson Geraldo de LimaDiniz MF, Dourado VA, Silva ME, Pedrosa ML, Bezerra FS and Wanderson Geraldo de Lima
  
  Cigarette smoking can lead to pivotal morphological changes in several human and animal tissues, especially when the exposure occurs during neonatal life. We evaluated the livers and spleens of C57BL/6 neonatal mice to determine possible morphological changes induced by exposure to cigarette smoke. In total, 15 C57BL/6 adult mice were used for mating, placing 2 female mice per male mouse for a 5-day period. Pregnant female mice were divided into 2 groups: the first group (ICS21) consisted of 5 female mice that were exposed to 4 cigarettes, 3 times daily for 21 days. They were subjected to 6 min of exposure per cigarette in an inhalation chamber. The second group (CG) consisted of 5 female mice that were not exposed to cigarette smoking and was used as a control group. Seven neonatal mice from both groups were weighed 24 h post-birth and then euthanize.. Read More»
  DOI: 10.4172/2157-7099.1000168

  Abstract PDF