Research Article
Hepatitis B Co-Infection is Associated with Poorer Survival of HIV-Infected Patients on Highly Active Antiretroviral Therapy in West Africa
Author(s): Nimzing G Ladep, Oche O Agbaji, Patricia A Agaba, Auwal Muazu, Placid Ugoagwu, Godwin Imade, Graham S Cooke, Livia Vivas, Sheena Mc Cormack, Simon D Taylor-Robinson, John Idoko and Phyllis KankiNimzing G Ladep, Oche O Agbaji, Patricia A Agaba, Auwal Muazu, Placid Ugoagwu, Godwin Imade, Graham S Cooke, Livia Vivas, Sheena Mc Cormack, Simon D Taylor-Robinson, John Idoko and Phyllis Kanki
Background: Hepatitis B has been reported to be high in HIV-infected African populations. However, the impact of this co-infection on the survival of HIV-infected Africans on long-term highly active antiretroviral therapy (HAART) remains poorly characterised. We investigated the impact of HBV/HIV co-infection on survival of HIV infected patients undergoing antiretroviral therapy in a West African population.
Methods: This was a clinic-based cohort study of HIV-infected adults enrolled in Nigeria, West Africa. Study subjects (9,758) were screened for hepatitis B and hepatitis C at HAART initiation. Kaplan-Meier survival and Cox proportional hazards models were used to estimate probability of survivaland toidentify predictors of mortality respectively, based on hepatitis B surface antigen status. All patients had signed an informed written consent before enrolment into the study.. Read More»
DOI:
10.4172/2155-6113.S3-006
Journal of AIDS & Clinical Research received 5264 citations as per Google Scholar report