Journal of Bioanalysis & Biomedicine

Sisir Nandi

Publications

• Research Article
  QSAR and Structure Based Molecular Docking of Angelicin Compounds: an Attempt to Drug Design against Swine Influenza
  Author(s): Muneer Alam and Sisir NandiMuneer Alam and Sisir Nandi
  
  There has been a great challenge of research and discovery of novel medicinal leads against swine influenza since 2009. Rational drug design utilizing pharmacoinformatics tools has been augmented now-a-days for in-silico screening of lead compounds prior to experimental synthesis, structural elucidation, biological evaluation and finally clinical trials to make the cost efficient drug design and discovery research. There is hardly any specific chemotherapeutics for the treatment against deadly swine influenza viral infection. Therefore, it is an urgent need to design and develop new anti-viral lead compounds active against swine influenza. Quantitative structure activity relationship (QSAR) has been used to develop models that correlate biological activity of angelicin compounds derived from published literature and their computed structural properties. The approach started by generat.. Read More»
  DOI: 10.4172/1948-593X.1000152

  Abstract PDF