Nuclear Medicine & Radiation Therapy

Sofia Meregalli

Publications

• Research Article
  Intracavitary Brachytherapy in Cervical Carcinoma: The Role of F18-FDGPET in Treatment Planning
  Author(s): Sofia Meregalli, Luca Guerra, Alessandra Zorz, Elisa Bonetto, Sarah Brenna, Gianluca Montanari, Elena De Ponti, Cristina Messa and Gianstefano GardaniSofia Meregalli, Luca Guerra, Alessandra Zorz, Elisa Bonetto, Sarah Brenna, Gianluca Montanari, Elena De Ponti, Cristina Messa and Gianstefano Gardani
  
  Objective: concomitant chemoirradiation with cisplatinum and intracavitary brachytherapy (BT) is the standard of care in patients with locally advanced cervix cancer. Treatment planning for BT provides for the use of three dimensional imaging, such as CT scan or MRI. Positron emission Tomography with [18F] FDG currently used in staging and restaging of this malignancy, is an imaging modality that can aid in image- guided radiation treatment planning. The purpose of our feasibility study was to compare two tumour volumes during BT planning, the CT-based and PET/CT-based clinical target volume (CTVs), in order to evaluate the value of functional imaging in BT planning and if it could be related to a CT standard data set. Moreover a correlation with some clinical data after a median follow up of 47 months is reported. Methods: From June 2007 to May 2010, thirteen women w.. Read More»
  DOI: 10.4172/2155-9619.S6-015

  Abstract PDF