Journal of Cytology & Histology

Soheil Ashkani-Esfahani

Publications

• Research Article
  Glucosamine Enhances Tissue Regeneration In The Process Of Wound Healing In Rats As Animal Model; A Stereological Study
  Author(s): Soheil Ashkani-Esfahani, Yasaman Emami, Elmira Esmaeilzadeh, Fereshteh Bagheri and Mohammad Reza NamaziSoheil Ashkani-Esfahani, Yasaman Emami, Elmira Esmaeilzadeh, Fereshteh Bagheri and Mohammad Reza Namazi
  
  Introduction: Glucosamine (GA), a water soluble hexosamine made from chitin or chitosan, was showed to have stimulatory effect on matrix formation, enhancing inflammatory response, modulating hyaluronic acid synthesis which promotes extracellular matrix remodeling leading to better wound healing. GA was also shown to have antioxidant and immunomodulatory effect which play roles in wound healing process. In this study we aimed to determine the effect of topical administration of GA on wound healing process in rats as animal model. Material and methods: 36 Wistar rats were divided into 3 groups; the control group which received no treatment; the Glucosamine group that received GA gel with 2% GA concentration, and the Base group that was treated with the vehicle. A 1 cm full-thickness wound was created on the posterior of each rat’s neck. Treatments took place every 24 hours for 15.. Read More»
  DOI: 10.4172/2157-7099.1000150

  Abstract PDF