Nigeria
Research Article
Possible Changes in Maternal Plasma Cortisol, AdrenocorticotropicHormones, Pregnancy Associated Plasma Protein-A and Alpha-fetoproteinin HIV Pregnant Women at NAUTH Nnewi, Nigeria
Author(s): Nkiruka Rose Ukibe, Charles Chinedum Onyenekwe, Amara Anulika Anojulu, Solomon Nwabueze Ukibe, Ezema Charles Ikechukwu, Friday Alphred Eghiagh Ehiaghe, Paul Isaac Emeje and Uchechukwu Anthonia EzugwuNkiruka Rose Ukibe, Charles Chinedum Onyenekwe, Amara Anulika Anojulu, Solomon Nwabueze Ukibe, Ezema Charles Ikechukwu, Friday Alphred Eghiagh Ehiaghe, Paul Isaac Emeje and Uchechukwu Anthonia Ezugwu
Background: There is limited information on if HIV infection induces stress in pregnancy. HIV can possibly contribute to the alterations in some fetal viability hormones thereby lead to adverse pregnancy outcome. The present study aimed to assess the possible changes in maternal cortisol, Adrenocorticotropic (ACTH), Pregnancy associated plasma protein-A (PAPP-A) and alpha-fetoprotein (AFP) hormone concentrations in HIV-infected pregnant women and their pregnancy outcomes.
Methods: A cross sectional study of 80 (Eighty) volunteer pregnant women aged (18-49) years recruited during routine antenatal clinics in Nnamdi Azikiwe Teaching Hospital, Nnewi, Anambra State, Nigeria was conducted. The participants were divided into groups: 40 (forty) apparently healthy pregnant and 40 (forty) HIV-infected pregnant women. 5 ml of morning blood samples wer.. Read More»
DOI:
10.4172/1948-593X.1000188
Journal of Bioanalysis & Biomedicine received 3099 citations as per Google Scholar report