Journal of Cytology & Histology

Sonia Marta Moriguichi

Publications

• Case Report
  Cytological Result of In Situ Ductal Carcinoma in Nipple Discharge: A Rare Diagnosis
  Author(s): José Cândido Caldeira Xavier-Júnior, Rafael Bispo Paschoalini, Rafael André Gonçalves Rosa, Vinicius Capistrano Ferreira, Mariangela Esther Alencar Marques, José Ricardo Paciência Rodrigues, Sonia Marta Moriguichi and Rozany Mucha DuflothJosé Cândido Caldeira Xavier-Júnior, Rafael Bispo Paschoalini, Rafael André Gonçalves Rosa, Vinicius Capistrano Ferreira, Mariangela Esther Alencar Marques, José Ricardo Paciência Rodrigues, Sonia Marta Moriguichi and Rozany Mucha Dufloth
  
  Background: More than half of women present nipple discharge during reproductive age. Case: This case is about a 36 years old woman with unilateral spontaneous hyaline nipple discharge associated with breast pain. The study of scintimammography was compatible with multifocal proliferative lesion in situ. It was performed cytological smear of nipple discharge. It was paucicellular smear represented by cluster of ductal cells in three-dimensional design with hyperchromatic nuclei in the presence of myoepithelial cells. Red cells and signs of necrosis were not observed. The diagnosis of in situ ductal carcinoma was confirmed in biopsy and mastectomy specimen through the expression of calponin in myoepithelial cells at immunohistochemistry. It is known that the cytological examination of nipple discharge has low sensitivity and specificity. Howeve.. Read More»
  DOI: 10.4172/2157-7099.1000284

  Abstract PDF