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Research Article
Oral Glucose Tolerance Testing identifies HIV+ infected women with
Diabetes Mellitus (DM) not captured by standard DM definition
Author(s): Sophie Seang, Jordan E Lake, Fang Tian, Kathryn Anastos, Mardge H Cohen and Phyllis C TienSophie Seang, Jordan E Lake, Fang Tian, Kathryn Anastos, Mardge H Cohen and Phyllis C Tien
Objective: HIV-infected (HIV+) individuals may have differential risk of diabetes mellitus (DM) compared to the general population, and the optimal diagnostic algorithm for DM in HIV+ persons remains unclear. We aimed to assess the utility of oral glucose tolerance testing (OGTT) for DM diagnosis in a cohort of women with or at risk for HIV infection.
Methods: Using American Diabetic Association DM definitions, DM prevalence and incidence were assessed among women enrolled in the Women’s Interagency HIV Study. DM was defined by 2-hour OGTT ≥ 200 mg/dL (DM_ OGTT) or a clinical definition (DM_C) that included any of the following: (i) anti-diabetic medication use or self-reported DM confirmed by either fasting glucose (FG) ≥126 mg/dL or HbA1c ≥ 6.5%, (ii) FG ≥ 126 mg/dL confirmed by a second FG ≥ 126 mg/dL or HbA1c 6.5%, or (iii) HbA1c 6.5.. Read More»
DOI:
10.4172/2155-6113.1000545
Journal of AIDS & Clinical Research received 5264 citations as per Google Scholar report