Advances in Robotics & Automation

Soumya B

Publications

• Research Article
  Optimal Strategies for Virus Propagation
  Author(s): Soumya BSoumya B
  
  This paper explores a number of questions regarding optimal strategies evolved by viruses upon entry into a vertebrate host. The infected cell life cycle consists of a non-productively infected stage in which it is producing virions but not releasing them and of a productively infected stage in which it is just releasing virions. The study explores why the infected cell cycle should be so delineated, something which is akin to a classic “bang-bang control” or all-or-none principle. The times spent in each of these stages represent a viral strategy to optimize peak viral load. Increasing the time spent in the non-productively infected phase (τ1) would lead to a concomitant increase in peak viremia. However increasing this time would also invite a more vigorous response from Cytotoxic TLymphocytes (CTLs). Simultaneously, if there is a vigorous antibody response, then we .. Read More»
  DOI: 10.4172/2168-9695.1000143

  Abstract PDF