Ragon Institute of MGH,
MIT and Harvard 400 Technology square, Cambridge MA 02139
Tanzania
Review Article
Lessons from Viral Superinfections for HIV-1 Vaccine Design
Author(s): Stephanie JostStephanie Jost
Superinfection refers to a second viral infection in the context of a pre-existing adaptive immune response to prior infection with a viral strain that has not been cleared, the two viruses being genetically distinct yet belonging to the same genus. As such, this phenomenon provides unique settings to gain insights into the immune correlates of protection against HIV-1. The focus of this review is to discuss the current knowledge about immune responses to HIV-1 and to other viruses that are associated with partial or complete immunity to superinfection, or lack thereof, and how that could be applied to future HIV-1 vaccine strategies.. Read More»
DOI:
10.4172/2155-6113.S3-005
Journal of AIDS & Clinical Research received 5264 citations as per Google Scholar report
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