Journal of Nephrology & Therapeutics

Suganthi Soundararajan

Publications

• Case Report
  A Rare and Atypical Case of Essential Cryoglobulinemic Glomerulonephritis with Crescents
  Author(s): Christopher Haas, Devinder Singh, Pedram Kohan, Suganthi Soundararajan and Sandeep AggarwalChristopher Haas, Devinder Singh, Pedram Kohan, Suganthi Soundararajan and Sandeep Aggarwal
  
  We report a rare and atypical case of essential cryoglobulinemic glomerulonephritis with crescent formation in an 18yo African-American male that presented with recurrent microscopic hematuria, proteinuria, and mildly elevated creatinine. There was no antecedent history of purpura, rashes, or arthralgia/ myalgia, and autoantibodies as well as viral serology for HCV, HIV, and CMV were negative. Quantification of serum immunoglobulins was significant for an elevated IgM without the presence of rheumatoid factor and elevated kappa and lambda light chains. Kidney biopsy demonstrated sclerosis, interstitial inflammation, endocapillary and mesangial proliferation, and crescent formation. Immunofluorescent studies demonstrated granular deposits within the glomerular basement membrane and mesangium. Electron microscopy revealed podocyte foot process effacement and.. Read More»
  DOI: 10.4172/2161-0959.1000220

  Abstract PDF