Medicinal Chemistry

Sujata V Lambe

Publications

• Commentary
  Synthesis of Some N-(4-(Aryl)-2-Thioxo-1,3-Thiazol-3(2H)-yl)Pyridine-4-Carboxamide as Antimicrobial and Anti-inflammatory Agents
  Author(s): Vikas G Rajurkar, Sujata V Lambe and Vinayak K DeshmukhVikas G Rajurkar, Sujata V Lambe and Vinayak K Deshmukh
  
  A series of potential bioactive compounds, N-(4-(aryl)-2-thioxo-1,3-thiazol-3(2H)-yl) pyridine-4-carboxamide has been synthesized and screened for antibacterial, antifungal, anti-inflammatory activity by minimum inhibitory concentration and protein denaturation method respectively. The compounds IIc and IIj were found to be broad spectrum antimicrobial agents at minimum inhibitory concentration value against E. coli, K. pneumonia, S. aureus, B. subtilis, A. nigar, and S. cerevisiae respectively. In anti-inflammatory activity, compounds IIc, IIf, IIh, and IIj at 100 mg/ml and compound IIl at 200 mg/ml were found significant active agent. .. Read More»
  DOI: 10.4172/2161-0444.1000276

  Abstract PDF