Clinical Depression

Sumayya Ayaz

Publications

• Review Article
  Translational Science of Psychosis in Parkinson’s Disease
  Author(s): Syeda Arshiya Farheen, Pooja Shah, Manpreet Gill, Sumayya Ayaz, Satneet Singh, Archana Adikey, Venkatesh Sreeram, Rizwan Ahmed, Mariyah Hussain and Saeed AhmedSyeda Arshiya Farheen, Pooja Shah, Manpreet Gill, Sumayya Ayaz, Satneet Singh, Archana Adikey, Venkatesh Sreeram, Rizwan Ahmed, Mariyah Hussain and Saeed Ahmed
  
  Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by loss of dopamine in the substantia nigra. It is predominantly a motor disorder but has shown to present with psychosis in few cases. Psychotic symptoms result from chronic treatment with few anti- Parkinson’s medications, ranging from depression, delusions to visual hallucinations, eventually progressing to auditory hallucinations in a few cases. Presence of psychotic symptoms with loss of insight is indicative of late stage of Parkinson’s disease and has poor prognosis. Accurate diagnosis of symptoms can be difficult due to significant overlapping clinical presentations which can be an admixture of underlying disease, exacerbation of pre-existing psychiatric illness or iatrogenic. The article below portrays the complex interplay between Parkinson’s disease psychosis, medicati.. Read More»
  

  Abstract PDF