Journal of Cytology & Histology

Sumeet Sehgal

Publications

• Research Article
  Value of Micronuclei Count as a Predictor of Cytotoxic Damage in Smoked and Smokeless Tobacco Users
  Author(s): Priya Jeyaraj and Sumeet SehgalPriya Jeyaraj and Sumeet Sehgal
  
  Background: Tobacco usage in the smoked and smokeless forms has reached epidemic proportions in the Asian sub-continent often leading to oral cancer which is the sixth most common cause of cancer related deaths globally. Micronuclei (MN) count is a promising indicator for the cytotoxic effects of tobacco usage. Our study was aimed at establishing a correlation between the MN counts among various tobacco habits. Methods: Exfoliated cells were collected over a period of three years from 2015 to 2017, from a total of 400 individuals consisting of 100 individuals each of smokers, gutkha chewers, khaini chewers and controls. PAP staining was done and the number of cells with micronuclei was counted under 40 X, by two independent examiners. The mean MN count was compared using the ANOVA test for statistical analysis. Results:.. Read More»
  DOI: 10.4172/2157-7099.1000495

  Abstract PDF