India
Research Article
Phenotypic Screening of Aminoglycoside Resistance and their Transferability in Clinical Isolates of Klebsiella pneumoniae from India
Author(s): Nargis Alom Choudhury, Sunanda Deb, Anand Prakash Maurya, Debadatta Dhar Chanda, Atanu Chakravarty and Amitabha BhattacharjeeNargis Alom Choudhury, Sunanda Deb, Anand Prakash Maurya, Debadatta Dhar Chanda, Atanu Chakravarty and Amitabha Bhattacharjee
Introduction: Klebsiella pneumonia is an emerging pathogen associated with multidrug resistance both in hospital and community settings. Aminoglycosides, considered to be second line drug for the treatment of such pathogens, become inactive due to acquisition of various resistance determinants by this organism.
Objective: The objective of the study was to screen the aminoglycoside resistant Klebsiella pneumonia from a tertiary referral hospital of northeast India and their transmission dynamics.
Method: A total of 177 consecutive, non-duplicate, clinical isolates of Klebsiella pneumonia were collected from patients from a period of September 2013 to February 2014. Screening for aminoglycoside resistance was performed. Transferability of aminoglycoside resistance was done by transformation assay. Genetic stability was che.. Read More»
DOI:
10.4172/2161-0703.1000218
Medical Microbiology & Diagnosis received 14 citations as per Google Scholar report