India
Review Article
Safety and Efficacy of New Oral Anticoagulants in Patients with Atrial Fibrillation: A Literature Review
Author(s): Shweta Bhatia, Supneet Sandhu and Dharinder TayalShweta Bhatia, Supneet Sandhu and Dharinder Tayal
Background: TraditionallyVitamin K antagonists (VKAs), such as warfarin, have been used to reduce the
risks of stroke and systemic embolism in patients with atrial fibrillation (AF). However, they are associated with increased risk of haemorrhage. Thus, there is a need for new oral anticoagulant agents that are effective, safe, and convenient to use. Recent, observational and randomized controlled clinical trials, have examined the long-term use and efficacy of new oral anticoagulants. However, their results pertaining to important secondary ef�cacy end points as well as safety outcomes were inconclusive.
Aim: We, therefore, performed a systematic review to examine the long-term ef�cacy and safety of the new oral anticoagulants namely; dabigatran, rivaroxaban and apixaban in patients with AF.
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DOI:
10.4172/2475-3211.1000101
Journal of Diabetic Complications & Medicine received 102 citations as per Google Scholar report