Journal of Metabolic Syndrome

Swarnalatha Guditi

Publications

• Research Article
  Evaluation of Glycemic, Lipid, Immune-Inflammatory and Oxidative Stress Markers in Various Clinical Stages of Type 2 Diabetic Nephropathy
  Author(s): Srilatha Reddy Gantala, Ramanjaneyulu Kummari, Mohini Ayiengar Tupurani, Rajesh Kumar Galimudi, Kishore Kumar Gundapaneni, Keerthi Kupsal, Nivas Shyamala, Surekha Rani Hanumanth and Swarnalatha GuditiSrilatha Reddy Gantala, Ramanjaneyulu Kummari, Mohini Ayiengar Tupurani, Rajesh Kumar Galimudi, Kishore Kumar Gundapaneni, Keerthi Kupsal, Nivas Shyamala, Surekha Rani Hanumanth and Swarnalatha Guditi
  
  Type 2 Diabetic nephropathy (DN), chronic multifactorial disorder is a devastating complication of DM and a main cause of end stage renal failure. A variety of factors like metabolic, hemodynamic, genetic and multiple pathogenic events contribute to the renal damage in type 2 DN. The present study was designed to assess blood glucose, serum lipid profiles, immune-inflammatory and oxidative stress markers in type 2 DN patients in different stages of the disease and healthy controls. Our study showed that FBS, PPG, HbA1c, TC, TG, LDL-C, ADA, CRP, MDA, NO and DNA damage were significantly high in type 2 DN patients (p<0.01) compared to controls. In stage wise comparison also FBS, PPG, HbA1c, LDL-C, CRP, MDA, NO and DNA damage showed significant difference (p<0.05). Further, a significant positive correlation was found between PLBS, LDL-C and CRP and oxidative stress markers (MDA, N.. Read More»
  DOI: 10.4172/2167-0943.1000237

  Abstract PDF