Molecular Biology: Open Access

Swati Bhowmick

Publications

• Research Article
  A Tale of Effectors; Their Secretory Mechanisms and Computational Discovery in Pathogenic, Non-Pathogenic and Commensal Microbes
  Author(s): Swati Bhowmick and Sucheta TripathySwati Bhowmick and Sucheta Tripathy
  
  Secretory proteins that are involved in modulating hosts are called as effectors. Lately, finding these important proteins from a large array of other gene products have been a focus area in many high funding research programs. However, since the biological data is accumulating at a much faster rate now than ever before, this search process can be compared to finding a needle in the haystack. Conventional laboratory-based methods require critical experiments, extended time and high cost which in many cases result in failure of testing hypothesis. Using high throughput sequencing technologies, whole genome sequences are generated much more quickly and efficiently. The avalanche of genomics data has ushered new opportunities into discovery of large number of novel extra cellular secretory proteins that usually lie undetected with conventional methods. Recently powerful bioinformatics me.. Read More»
  DOI: 10.4172/2168-9547.1000118

  Abstract PDF