Journal of Pharmacognosy & Natural Products

Syamsudin Abdillah

Publications

• Research Article
  Antidiabetic Activity of Flavonoid from Binahong Leaves (Anredera cordifolia) Extract in Alloxan Induced Mice
  Author(s): Ratna Djamil, Wiwi Winarti, Sarah Zaidan and Syamsudin AbdillahRatna Djamil, Wiwi Winarti, Sarah Zaidan and Syamsudin Abdillah
  
  Objective: To evaluate antidiabetic activitiy of flavonoid from binahong (Anredera cordifolia) leaves. Method: α-glycosidase enzyme inhibiting activity was tested in vitro and antidiabetic activity in alloxan-induced mice. Results: The research shows that ethyl acetate extract of binahong leaves had α-glycosidase enzyme inhibition of 81,23 μg/mL. Isolation of active compounds in binahong leaves successfully identified flavonoid compound of 8- Glucopyranosyl-4',5,7-trihydroxyflavone, which is also known as 8-Glucopyranosylapigenin. 8-Glucosylapigenin that is also popularly known as Orientoside was found to have α-glycosidase enzyme inhibiting activity with IC50 value of 20, 23 μg/mL and have an ability to decrease blood glucose in alloxan-induced mice. Conclusion:.. Read More»
  DOI: 10.4172/2472-0992.1000139

  Abstract PDF