Jazan
Saudi Arabia
Research Article
Studies on Hepato and Renal Toxicity of Cadmium on Normal and Protein Malnourished Rats
Author(s): Syed Saleem HusainSyed Saleem Husain
Cadmium is an established toxic metal with its ability to accumulate in blood, liver and kidney. It adversely affects the renal cortex and ultimately leads to the renal failure. It has been reported that deficiency of certain dietary components affects cadmium toxicity. Present study was designed to evaluate the cadmium toxicity (50 ppm in drinking water) in protein malnourished group (8%) and on normal protein (21%) diet groups. It was found that Cd exposure led to marked elevation in alkaline phosphatase, acid phosphatase, glutamic pyruvic transferase, glutamic oxaloacetic acid transferase with significant increase in protein malnourished group (p 0.005).
Same trend of result was noted in urinary concentration of alpha amino acid, albumin, total protein and glucose. Results were more significant (p 0.001) in malnourished animals. However, hepatic and renal enzymes showed depl.. Read More»
DOI:
10.4172/2169-0022.1000129
Journal of Material Sciences & Engineering received 3677 citations as per Google Scholar report