Journal of Bioprocessing & Biotechniques

T. J. Burdock

Publications

• Research Article
  A Dehydrogenase Activity Test for Monitoring the Growth of Streptomyces Venezuelae in a Nutrient Rich Medium
  Author(s): T. J. Burdock, M.S. Brooks and A.E. GhalyT. J. Burdock, M.S. Brooks and A.E. Ghaly
  
   Jadomycin is a novel antibiotic that has shown activities against bacteria, yeasts and fungi as well as cytotoxic properties to cancer cells. Because of the wide range of its inhibitory actions, jadomycin shows promise as a novel antibiotic and cancer treatment drug. Streptomyces venezuelae are aerobic bacteria that are capable of producing jadomycin when shocked by alcohol in a nutrient deprived amino acid rich medium. The size of the bacterial population that is transferred from the growth medium to the production medium can significantly affect the jadomycin yield. Therefore, the number of transferred bacteria must be accurately measured. In this study, a dehydrogenase activity measurement test was developed for S. venezuelae using triphenyl tetrazolium chloride (TTC) to measure the cell growth and activity in maltose-yeast extract-malt extr.. Read More»
  DOI: 10.4172/2155-9821.1000101

  Abstract PDF