Department of Epidemiology and Biostatistics, Institute of Public Health,
Ethiopia
Research Article
Rate of Immunological Failure and its Predictors among Patients on Highly Active Antiretroviral Therapy at Debremarkos Hospital, Northwest Ethiopia: A Retrospective Follow up Study
Author(s): Yayehirad Alemu Melsew, Mamo Wubshet Terefe, Gizachew Assefa Tessema and Tadesse Awoke AyeleYayehirad Alemu Melsew, Mamo Wubshet Terefe, Gizachew Assefa Tessema and Tadesse Awoke Ayele
Background: In a resource-limited setting, patients on antiretroviral treatment are monitored by using immunological and clinical assessment due to the inaccessibility of viral load monitoring. The aim of this study was to assess the rate and predictors of immunological failure among patients taking highly active antiretroviral treatment at Debremarkos hospital, Northwest Ethiopia.
Methods: Retrospective follow up study was conducted at Debremarkos hospital on 509 adults who had started antiretroviral treatment during the period between January 01, 2007 and April 01, 2008. Data were analyzed using SPSS version 20. Life table and Kaplan-Meier curve was used to estimate the cumulative probablities and median time for immunologic failure respectively. Cox proportional hazard model was fitted to compute hazard ratios with their 95% confidence intervals.
Result: The median .. Read More»
DOI:
10.4172/2155-6113.1000211
Journal of AIDS & Clinical Research received 5264 citations as per Google Scholar report