Chang Gung Memorial Hospital at Linkou and Taipei,
Taiwan, 5, Fu-Shin Street, Kweishan, Taoyuan 333
People’s Republic of China
Research Article
Isolated Myeloid Sarcoma of the Maxillary Sinus: A Case Report and Review of Literature
Author(s): Chi-Kuang Young, Tuan-Jen Fang, Yushin-Hung, Wen-Yu Chuang and Ta-Jen LeeChi-Kuang Young, Tuan-Jen Fang, Yushin-Hung, Wen-Yu Chuang and Ta-Jen Lee
Myeloid sarcoma is a rare malignant disease defined as extramedullary infiltration of immature myeloid cells and may precede or occur synchronously with acute myeloid leukemia. We reported a 35-year-old male of isolated myeloid sarcoma who presented with symptoms similar to chronic rhinosinusitis initially. Isolated myeloid sarcoma in the paranasal sinuses is exceedingly rare after reviewing the previous literatures. Through proper histological, adequate panels of immunohistochemical stain (positive markers including CD68/KP1, myeloperoxidase, CD 117, CD 99, CD68/PG-M1, lysozyme, CD34, terminal deoxynucleotidyl transferase and negative markers including CD3, CD20, CD45RO and CD79a) and cytogenic study lead to accurate diagnosis. Early intervention with systemic chemotherapy with cytarabine-based regimens is the treatment of choice. The role of chromosomal aberrations and genetic abnor.. Read More»
DOI:
10.4172/2157-7099.1000234
Journal of Cytology & Histology received 2334 citations as per Google Scholar report