Japan
Research Article
The Outcome of Surgery in Patients with Growth Hormone Secreting Adenomas: Early Surgical Sntervention is Essential for improving the Surgical Cure Rate
Author(s): Hidetoshi Ikeda, Shunsuke Sato, Toshiyuki Saginoya, Takamasa Kudo and Kazuo WatanabeHidetoshi Ikeda, Shunsuke Sato, Toshiyuki Saginoya, Takamasa Kudo and Kazuo Watanabe
Object: During the last 10 years, 129 consecutive transsphenoidal operations for growth hormone (GH) secreting pituitary adenomas have been carried out. In the present study, 120 of the patients involved in these operations have been reviewed to evaluate the accuracy of diagnosis of adenoma, the cure rate, and to ascertain the favorable surgical effects of early surgical intervention.
Methods: A total of 120 GH secreting adenomas, including 95 patients with typical acromegaly and 25 patients with no apparent clinical features of acromegaly, were evaluated. The pituitary tumors were investigated by means of Magnetic Resonance (MR) imaging at 1.5T and 3T, composite 3T-MRI and [11C] Methionine-positron Emission Tomography (MET-PET) imaging and histological and immunohistochemical staining. The modern remission criteria (a glucose suppressed [na.. Read More»
DOI:
10.4172/2167-0943.S2-001
Journal of Metabolic Syndrome received 48 citations as per Google Scholar report