Japan
Research Article
Categorized Preoperative Estimated Glomerular Filtration Rate as a Criterion for Choosing Between Radical or Partial Nephrectomy for Renal Tumor
Author(s): Tsuyoshi Yamaguchi, Takatsugu Okegawa, Eiji Higashihara and Kikuo NutaharaTsuyoshi Yamaguchi, Takatsugu Okegawa, Eiji Higashihara and Kikuo Nutahara
Purpose: We examined retrospectively whether outcomes of radical nephrectomy (RN) and partial nephrectomy (PN) are predictable on the basis of preoperative estimated glomerular filtration rate (eGFR) classifications. Material and methods: The study included 284 patients with renal tumor who underwent RN (n=195) or PN (n=89) at our institution. Preoperative eGFRs were categorized to reflect the stages of chronic kidney disease (CKD). The primary endpoint was postoperative onset of CKD stage 3b (eGFR<45 mL/min/1.73 m2). Also examined were the incidence of postoperative cardiovascular (CV) events, overall survival (OS), and cause-specific survival (CSS). The outcomes of RN and PN were compared per the preoperative eGFR categories. Results: PN was found to prevent postoperative CKD ≥ stage3b when the preoperative eGFR indicated CKD stage 2. The incidence of CV events was significan.. Read More»
DOI:
10.4172/2161-0959.1000259
Journal of Nephrology & Therapeutics received 784 citations as per Google Scholar report