Japan
Research Article
Evaluation of Response to Steroid Therapy for Cardiac Sarcoidosis Using Volumetric Analysis of 18F-FDG PET/CT
Author(s): Yasuhiro Maruoka, Michinobu Nagao, Shingo Baba, Takuro Isoda, Yoshiyuki Kitamura, Satoshi Kawanami, Yuzo Yamasaki, Masayuki Sasaki, Tomomi Ide, Kenichi Hiasa and Hiroshi HondaYasuhiro Maruoka, Michinobu Nagao, Shingo Baba, Takuro Isoda, Yoshiyuki Kitamura, Satoshi Kawanami, Yuzo Yamasaki, Masayuki Sasaki, Tomomi Ide, Kenichi Hiasa and Hiroshi Honda
Background: The purpose of this study was to investigate the utility of total lesion glycolysis (TLG) in 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) to predict the response to steroid therapy for cardiac sarcoidosis (CS).
Methods: Thirty-six patients with clinically suspected CS who had undergone 18F-FDG PET/CT were retrospectively analysed. Of the 36 patients, 21 were diagnosed as having CS according to Japanese Ministry of Health and Welfare guidelines and divided into 12 responders and 9 non-responders after steroid therapy by the mean follow-up period of 19 months. SUVmax and total lesion glycolysis (TLG) for the left ventricle (LV) on 18F-FDG PET/CT were compared between responders and non-responders using the Wilcoxon test. The predictability of response to steroid therapy was analysed using.. Read More»
DOI:
10.4172/1948-593X.1000184
Journal of Bioanalysis & Biomedicine received 3099 citations as per Google Scholar report