Nigeria
Research Article
Prevalent Hepatitis B Virus Genotypes Circulating among HIV Co-Infected Patients in an Urban City, South-South Nigeria
Author(s): Ayodele MBO, Ogugbue CJ, Frank-Peterside P and Tatfeng YMAyodele MBO, Ogugbue CJ, Frank-Peterside P and Tatfeng YM
Hepatitis B Virus (HBV) has been classified into genotypes A-J which characteristically has different geographic
origins, disease progression and responses to antiviral treatment. Co-infection caused by Human immunodeficiency
virus (HIV) and HBV is common because they both share similar routes of transmission. In this study, we report the
prevalent HBV genotypes circulating among HBV-HIV co-infected patients in Port Harcourt, south-south Nigeria.
DNA was extracted from stored serum samples obtained from 25 HBV-HIV co-infected patients selected out of 535
HIV I/II sero-positive patients confirmed to be HBsAg positive from University of Port Harcourt Teaching Hospital
(UPTH) and Obio Cottage Hospital both in Port Harcourt City. HBV genotyping was carried out using a nested
Polymerase Chain Reaction (PCR) approach followed by Big-dye termination sequencing. The mega .. Read More»
Journal of AIDS & Clinical Research received 5264 citations as per Google Scholar report