Journal of Nephrology & Therapeutics

Tatjana Sotirova

Publications

• Research Article
  Renal Enzymes and Microglobulins in Patients with Rheumathoid Arthritis
  Author(s): Dejan Spasovski and Tatjana SotirovaDejan Spasovski and Tatjana Sotirova
  
  Aim: The aim of this study was to detect and compare the enzymes, globulins and reactants of the early phase in patients with untreated rheumatoid arthritis and to reveal the effect of untreated rheumatoid arthritis on tubular function and sensitivity on brush border area. Material and Methods: The samples of serum and urine were examined in 70 participants (35 patients with untreated rheumatoid arthritis, 35 individuals of the healthy control group). We used in the study the kinetic assay for determination of alanine aminopeptidase (AAP) (Standards methods under IFCC), γ-glutamiytransferase and MEIA (Microparticle Enzyme Immunoassay) (Abbot Axsym system) for detection of β 2-microglobulin in urine. Results: Of 35 patients with RA, 16 patients showed presence of γ-GT (sensitivity of the test - 45.71%), 24 patients showed presence of AAP en.. Read More»
  DOI: 10.4172/2161-0959.1000185

  Abstract PDF