Journal of Nephrology & Therapeutics

Tausif Zar

Publications

• Case Report
  Focal Segmental Glomerulosclerosis Associated Seronegative Antiphospholipid Syndrome
  Author(s): Tausif Zar, Wilner Samson, Ann Parke, M Melinda Sanders and Harold T. YamaseTausif Zar, Wilner Samson, Ann Parke, M Melinda Sanders and Harold T. Yamase
  
  Secondary Focal Segmental Glomerulosclerosis (FSGS) from thrombotic microangiopathies including Antiphospholipid Antibody Syndrome (APS), is well documented. We present a case with clinical features of APS but consistently negative serologies, suggesting ‘Seronegative APS (SNAPS)’. The patient was evaluated at the Division of Nephrology, University of Connecticut Health Center for progressive Chronic Kidney Disease (CKD). A renal biopsy exhibited thrombotic microangiopathy and associated FSGS. Systemic thrombophilia can be primary or secondary and has an extensive list of differential diagnoses. Distinct clinical features and serologic markers characterize a particular etiology. Antiphospholipid Syndrome (APS) is the most common acquired thrombophilia. Serologic evidence of APS is the presence of commonly recognized antibodies to phospholipids in this syndrome i.e... Read More»
  DOI: 10.4172/2161-0959.1000123

  Abstract PDF