Medanta Cancer Institute,
Medanta- The Medicity, Gurgaon-122001
India
Research Article
A Comparison of Fluro-Deoxy Glucose-Positron Emission Tomography (FDGPET)Versus Magnetic Resonance (MR) Based Target Volume Delineation in
Post-operative Glioblastoma
Author(s): Tejinder Kataria, Kuldeep Sharma, Pranav Chadha, Dhanraj Jangid and Kulbir AhlawatTejinder Kataria, Kuldeep Sharma, Pranav Chadha, Dhanraj Jangid and Kulbir Ahlawat
Abstract
Background: Glioblastoma is the commonest brain tumor of adults carrying a very poor prognosis. Targeting the tumor accurately during surgery and radiotherapy holds promise in future. PET with various tracers is being explored worldwide to enhance the accuracy of target delineation. This study was undertaken to evaluate the differences and correlation between the target volumes delineated by using MRI and 18F-FDG PET during RT planning and to evaluate whether inclusion of PET is helpful in better coverage of high risk area for recurrence.
Materials and Methods: Fifteen post-operative patients of glioblastoma were prospectively enrolled. Planning images were acquired with CT, MRI and delayed PET. Image fusion was done to delineate MR-based (GTV-MR, CTV-MR, PTV-MR), PET-based (GTV-PET, CTV-PET) and combined (GTV-X, CTV-X) volu.. Read More»
DOI:
10.4172/2155-9619.1000205
Nuclear Medicine & Radiation Therapy received 706 citations as per Google Scholar report
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