Molecular Biology: Open Access

Tekeba Sisay

Publications

• Review Article
  Drug Resistance Mechanisms and Molecular Diagnosis Methods for Tuberculosis
  Author(s): Tekeba Sisay, Nega Berhane and Deepak VermaTekeba Sisay, Nega Berhane and Deepak Verma
  
  Mycobacterium tuberculosis is the main cause of death worldwide. It has been thought that one third of the world population has been infected with Mycobacterium tuberculosis (MTB). To assure effective treatment, TB is treated with a combination of anti-TB drugs in the strategy called directly observed treatment short-course (DOTS), which is a treatment regimen that may, lasts from six to eight months. Even though DOTS strategy and effective chemotherapy are used in the past decades, drug-resistant TB is the worldwide problem since the introduction of chemotherapy. Especially, drug resistance is recognized as a worldwide problem after the dramatic outbreaks of Multidrug-resistant Mycobacterium tuberculosis (MDR-TB) strains. MDR-TB is a type of drug resistant TB which is developed when MTB strains can withstand at least two potential anti-TB antibiotics, isoni.. Read More»
  

  Abstract PDF