Pulmonary & Respiratory Medicine

Tetsutaro Nagaoka

Publications

• Research Article
  Efficacy of Antibiotic Prophylaxis after Endobronchial Ultrasound-guided Transbronchial Needle Aspiration: A Preliminary Prospective Study
  Author(s): Haruhi Takagi, Tetsutaro Nagaoka, Katsutoshi Ando, Takeo Tsutsumi, Masako Ichikawa, Ryo Koyama, Naoko Shimada, Kazunori Tobino and Kazuhisa TakahashiHaruhi Takagi, Tetsutaro Nagaoka, Katsutoshi Ando, Takeo Tsutsumi, Masako Ichikawa, Ryo Koyama, Naoko Shimada, Kazunori Tobino and Kazuhisa Takahashi
  
  Background: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is useful for diagnosing mediastinal and hilar lymphadenopathy. While bacteremia and serious infectious complications after EBUS-TBNA have been reported, the efficacy of antibiotic prophylaxis is unclear. This preliminary prospective study aimed to evaluate the efficacy of antibiotic prophylaxis after EBUS-TBNA. Methods: Patients were randomly assigned to the antibiotic group (n = 43) or control group (n = 47). Ampicillin/ sulbactam was intravenously administered before the puncture, followed by oral amoxicillin/clavulanate. The primary outcome was body temperature (BT) within 5 days after EBUS-TBNA. The secondary outcomes were the change in the white blood cell count (WBC) and C-reactive protein (CRP) value before and after the examination, and the freq.. Read More»
  DOI: 10.4172/2161-105X.1000416

  Abstract PDF