Journal of Hypertension: Open Access

Tetsuya Watanabe

Publications

• Research Article
  Analysis of the Difference in the Pressure-Natriuresis Relationship Based on the Class of Medication Using Spot Urine Tests in Hypertensive Patients
  Author(s): Shiro Hoshida, Takafumi Nakagawa, Yukinori Shinoda, Hirooki Inui and Tetsuya WatanabeShiro Hoshida, Takafumi Nakagawa, Yukinori Shinoda, Hirooki Inui and Tetsuya Watanabe
  
  Objective: We estimated the daily sodium intake using a spot urine method in hypertensive patients, and investigated the differences in the pressure-natriuresis relationship depending on the type of medications and the involvement of renal function in this relationship. Methods: This study included 356 spot urine samples of hypertensive patients at our cardiology outpatient clinic. Daily sodium intake was estimated by the spot urine tests at the time of study enrolment. We examined the difference in the relationships among estimated daily sodium intake, mean blood pressure (mBP), and estimated glomerular filtration rate (eGFR) with each medication. Results: In multivariate analysis, the eGFR and mBP were significantly associated with estimated daily sodium intake. The slope of the pressure-natriuresis relationship was steeper in patients treated with renin-angioten.. Read More»
  DOI: 10.4172/2167-1095.1000154

  Abstract PDF