India
Research Article
Recent Development in Finite Element Methods and Computer Aided Design in the Development of Porous Scaffolds-A Review
Author(s): Nitin Sahai and Tewari RPNitin Sahai and Tewari RP
Tissue engineering the development of functional substitute to replace missing or malfunctioning human tissue and organs by using biodegradable biomaterials as scaffolds to direct specific cell types to organize into three dimensional structures and perform differentiated function of targeted tissue. The important factors to be considered in designing of microstructure were porosity, pore size, and pore structure with respect to nutrient supply for transplanted and regenerated cells. Performance of various functions of the tissue structure depends on porous scaffold microstructures with specific porosity, pore size, characteristics that influence the behavior of the incorporated cells. Finite element Methods (FEM) and Computer Aided Design (CAD) combines with manufacturing technologies such as Solid Freeform Fabrication (SFF) helpful to allow virtual design, characterization and produ.. Read More»
DOI:
10.4172/2157-7552.1000113
Journal of Tissue Science and Engineering received 807 citations as per Google Scholar report