China
Research Article
Coding by Different Diameter Impedance, Detection Method of Microspheres Which are Used to Produce Liquid Biochip
Author(s): Zhanke Wang, Tian Hu, Xiaolu Hu, Tao Song, Wangshen Lei, Honghua Zhou, Xiao Yan, Hong Dai and Jin ChangZhanke Wang, Tian Hu, Xiaolu Hu, Tao Song, Wangshen Lei, Honghua Zhou, Xiao Yan, Hong Dai and Jin Chang
This research was aiming at developing liquid biochip which was coded by impedance microsphere of different diameter and providing research foundation for its detecting device. Adopting the method of loading constant current source between both ends of micropore in ruby, it were tested that three sorts of microspheres’ impedance with particle sizes of 2μm, 5μm, 10μm. It was resultantly found that microsphere diameter is in direct proportion to impedance and voltage between both ends of micropore. In other words, microsphere of different size could be distinguished from each other by their impedance. Our research drew the indication that impedance of microspheres in different sizes could be theoretically calculated as well as measured and automatically distinguished, offering experimental and theoretical foundation for liquid biochip development... Read More»
DOI:
10.4172/2155-6210.1000111
Biosensors & Bioelectronics received 1751 citations as per Google Scholar report