Research Article
Immunological and Virological Outcomes at 5 Years in HIV Infected Adults Who Start HAART at a CD4 Cell Count of Less Than 200 in Barbados
Author(s): Alok Kumar, Krishna R Kilaru and Timothy C RoachAlok Kumar, Krishna R Kilaru and Timothy C Roach
Objective: To assess the immunologic and virological response after 5 years of highly active antiretroviral therapy (HAART) in treatment naive HIV-1 infected adults presenting late in the course of their disease.
Design: Prospective long term observational study. The response to HAART is described in HIV-1 infected ARV naïve adults initiating treatment at CD4+ cell counts < 200 during June 2005 through December 2005 in Barbados, West Indies. Baseline values as well as 5 years post-HAART values for CD4+ cell counts and viral load were recorded for the cohort.
Results: 50 ARV naïve HIV-1 infected adults initiated treatment when their CD4+ cell count was, 200. Most received Combivir plus Nevirapine or Efavirenz. At the baseline, their median CD4+count was 36 cells/μL (IQ Range:15-82) and their median viral load was at 75,000 (4.87 log1.. Read More»
DOI:
10.4172/2155-6113.1000406
Journal of AIDS & Clinical Research received 5264 citations as per Google Scholar report