Neurological Disorders

Timothy SK Chan

Publications

• Case Report
  Symptomatic Metastasis to the Pituitary Gland: A Report of Three Cases and Review of the Literature
  Author(s): Peter YM Woo, Ronald Li, Yung Chan, Timothy SK Chan, Peter KH Pang, Kwong-Yau Chan and John CK KwokPeter YM Woo, Ronald Li, Yung Chan, Timothy SK Chan, Peter KH Pang, Kwong-Yau Chan and John CK Kwok
  
  Objective and importance: Symptomatic metastases to the pituitary gland are rare and often herald advanced systemic malignant disease. Distinguishing them from benign pituitary adenomas is challenging. The clinicoradiological features of three patients with pituitary metastases are presented. We also review the literature from 1970 to 2015 to formulate a diagnostic strategy. Clinical presentation: All patients were elderly with ages ranging from 65 to 82 years old. One had a previously undiagnosed prostatic carcinoma and two had known histories of primary gastric or parotid salivary gland carcinoma. Rapid visual deterioration was the most common symptom followed by ophthalmoplegia. Cranial diabetes insipidus (CDI) was observed after administrating hydrocortisone replacement in one patient. All patients had evidence of a solitary pituitary tumor on magnetic resonance imaging (MRI) of w.. Read More»
  DOI: 10.4172/2329-6895.1000236

  Abstract PDF