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Research Article
Small Fiber Neuropathy in Patients Meeting Diagnostic Criteria for Fibromyalgia
Author(s): Todd D Levine, David S Saperstein, Aidan Levine, Kevin Hackshaw and Victoria LawsonTodd D Levine, David S Saperstein, Aidan Levine, Kevin Hackshaw and Victoria Lawson
Introduction: The cause for fibromyalgia (FM) is unknown and diagnostic criteria can be nonspecific. Many patients with FM have nonspecific sensory symptoms consistent with a neuropathic process. Previous studies have shown that a significant percentage of patients diagnosed with FM have small fiber neuropathy (SFN) based on decreased intraepidermal nerve fiber density (IENFD) on according to punch skin biopsy testing. The purpose of this study was to demonstrate that punch skin biopsy testing is an effective way to identify SFN and its underlying causes in patients previously diagnosed with FM.
Methods: We studied 56 patients referred to peripheral nerve disease centers for evaluation of neuropathic pain who met the diagnostic criteria for FM. All underwent punch skin biopsy testing. If SFN was detected, patients underwent further laborator.. Read More»
DOI:
10.4172/2329-6895.1000305
Neurological Disorders received 1343 citations as per Google Scholar report