Journal of Clinical Case Reports

Tokio Sugiura

Publications

• Case Report
  Viral Load Before and After Exchange Transfusion in a Neonate with Hyperbilirubinemia and Congenital Cytomegalovirus Infection
  Author(s): Kei Ohashi, Koichi Ito, Takeshi Endo, Tokio Sugiura, Risa Awaya, Tatenobu Goto, Yoshiaki Nagaya, Hiroko Ueda, Rika Nagasaki, Takenori Kato and Shinji SaitohKei Ohashi, Koichi Ito, Takeshi Endo, Tokio Sugiura, Risa Awaya, Tatenobu Goto, Yoshiaki Nagaya, Hiroko Ueda, Rika Nagasaki, Takenori Kato and Shinji Saitoh
  
  Introduction: Cytomegalovirus is the most common cause of intrauterine infection in developed countries. Between 10% and 15% of infants infected with congenital cytomegalovirus exhibits the clinically apparent or symptomatic form of the disease. Exchange transfusion is an established therapy for hyperbilirubinemia and severe anemia. However, to the best of our knowledge, the viral load of cytomegalovirus before and after exchange transfusion has not been previously reported. Case report: A Japanese female was delivered at 36 weeks of gestation to a 29-year-old gravida 3 para 3 by emergency Cesarean section because of non-reassuring fetal status. Hepatomegaly, splenomegaly, generalized petechiae, leptocephaly, and jaundice were noted at birth. On admission, her total bilirubin was 14.2 mg/dL, cytomegalovirus immunoglobulin M was positive (4.63 mg/dL), and her head ultrasound .. Read More»
  DOI: 10.4172/2165-7920.1000343

  Abstract PDF