Germany
Research Article
Osteogenic Potential of Oxycellulose: A Molecular-Biological and Histological Study in Rats
Author(s): Christiane Kunert-Keil, Jakub Hadzik, Isabel Grewe, Ute Botzenhart, Marzena Dominiak, Tomasz Gedrange and Tomasz GredesChristiane Kunert-Keil, Jakub Hadzik, Isabel Grewe, Ute Botzenhart, Marzena Dominiak, Tomasz Gedrange and Tomasz Gredes
Oxidized cellulose is a polysaccharide substance formed by the oxidation of cellulose. Depending on the amount used, oxycellulose is completely absorbable and can be used as hemostatic agents in general and dental surgery for hemostatic purposes. Each procedure on the bone also carries the risk of bleeding, but still not much is known about the bone tissue reaction on this material. Due to this fact, the aim of this study was to evaluate the tissue reaction and osteogenic potential of the natural oxycellulose material RESORBA-CELL® standard by its implantation into rat cranial bone defects. The materials were evaluated using an established rat cranial defect model in 22 animals. One bone defect with a diameter of 5 mm was created per animal. The defects were filled with oxycellulose and left to heal for 4 weeks. Twelve samples (n=6 oxycellulose; n=6 untreated control lesions) were.. Read More»
DOI:
10.4172/2157-7099.1000304
Journal of Cytology & Histology received 2476 citations as per Google Scholar report