Journal of Nephrology & Therapeutics

Tomislav Kurelac

Publications

• Research Article
  Serum Bone Markers and Coronary Artery Calcification in End Stage Renal Failure Patients and Kidney Transplant Recipients
  Author(s): Tanja Celic, Josip Spanjol, Antun Grskovic, Melita Kukuljan, Sanjin Racki, Tomislav Kurelac, Ivana Marić and Dragica BobinacTanja Celic, Josip Spanjol, Antun Grskovic, Melita Kukuljan, Sanjin Racki, Tomislav Kurelac, Ivana Marić and Dragica Bobinac
  
  Background: Variety of growth factors and cytokines are involved in the process of bone turnover. Evidences are showing that alterations in OPG/RANK/RANKL system form the basis of many metabolic diseases. So, we evaluated the relationship between OPG and RANKL levels, to establish a possible relationship with other bone markers and coronary artery calcification. Methods: Patients with chronic kidney disease and patients during the first year after transplantation had coronary artery scan and their blood was analyzed for serum bone markers. The following serum markers were measured: OPG, RANKL, BAP, TRAP5b and iPTH. Results: All measured bone markers values increased with the disease progression and return to normal values during the first year after transplantation. Serum values of OPG, BAP, TRAP5b and iPTH are influence.. Read More»
  DOI: 10.4172/2161-0959.1000125

  Abstract PDF